Interactions of propofol and remifentanil on bispectral index under 66% N2O: analysis by dose-effect curve, isobologram, and combination index
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چکیده
منابع مشابه
Interactions of propofol and remifentanil on bispectral index under 66% N2O: analysis by dose-effect curve, isobologram, and combination index
BACKGROUND Propofol and remifentanil are usually co-administered and have shown synergistic effect for anesthesia. However, the synergistic effect of the two drugs on hypnosis measured by bispectral index (BIS) was controversial in previous studies. The aim of this study was to identify the interaction of propofol and remifentanil on BIS and the optimal dose combinations for hypnosis under 66% ...
متن کاملEffect of remifentanil on plasma propofol concentration and bispectral index during propofol anaesthesia.
BACKGROUND Propofol and remifentanil are commonly administered together in clinical anaesthesia, but the effect of remifentanil on the plasma concentration of propofol has yet to be established. The aim of the present study was to investigate the effect of remifentanil on plasma propofol concentrations (Cp) in the absence of surgical stimulation. METHODS Thirty-eight patients undergoing elect...
متن کامل[Anesthesia recovery comparison between remifentanil-propofol and remifentanil-desflurane guided by Bispectral Index® monitoring].
BACKGROUND AND OBJECTIVES There is a strong demand for fast and predictable anesthesia recovery with few side effects. Choice of the hypnotic agent could impact on that. This study investigated the differences between recoveries after remifentanil-propofol and remifentanil-desflurane anesthesias guided by bispectral index (BIS®). METHODS Forty patients were randomly assigned into 2 groups acc...
متن کاملTreatment of different-aged children under bispectral index monitoring with intravenous anesthesia with propofol and remifentanil.
OBJECTIVE To investigate the changes in bispectral index (BIS) to determine the controllability and safety of intravenous anesthesia with propofol and remifentanil in different-aged children. PATIENTS AND METHODS Forty cases of ASA levels I or II were divided into four groups (A group, ≤ three months old; B group, three months to two years old; C group, two years to six years old; and D group...
متن کاملEffect of sugammadex or neostigmine neuromuscular block reversal on bispectral index monitoring of propofol/remifentanil anaesthesia.
BACKGROUND Sugammadex is a modified γ-cyclodextrin with a novel mechanism of action for reversing the steroidal neuromuscular blocking agent rocuronium. Bispectral index (BIS) is an EEG-derived measure which can be sensitive to frontal electromyographic (EMG) artifacts. We compared BIS values before and after sugammadex or neostigmine neuromuscular block (NMB) reversal in patients with or witho...
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ژورنال
عنوان ژورنال: Korean Journal of Anesthesiology
سال: 2010
ISSN: 2005-6419,2005-7563
DOI: 10.4097/kjae.2010.59.6.371